How-to Guide


Are SARMs Safe? A Look at the Potential Side Effects

If you’re into bodybuilding, you are probably familiar with the craze around SARMs. These synthetic compounds work as magic bullets for building muscle and improving performance. 

But are SARMs safe? Do they have any severe side effects? Do they cause damage to your body organs? This article discusses it all.

So, without further ado, let’s quickly jump in.

SARMs and their potential benefits 

Simply stated, SARMS are like keys that unlock specific doors in your body. These doors are androgen receptors, which control male characteristics like muscle growth. 

SARMs selectively bind to these receptors and trigger muscle-building effects in your body. It improves your overall physique and performance. Unlike traditional steroids, which affect various tissues, SARMs offer targeted action, minimizing unwanted side effects.

Potential Benefits of SARMs

SARMs offer various benefits, such as:

  • Muscle Growth: SARMs can accelerate muscle growth, helping you achieve your fitness goals faster.
  • Fat Loss: Some SARMs may promote fat burning, leading to a leaner and more sculpted physique.
  • Increased Bone Density: SARMs may improve bone strength, reducing the risk of fractures.
  • Improved Performance: SARMs can enhance athletic performance, giving you an edge in your chosen sport.

Side Effects of SARMs

While SARMS have promising benefits, they often come with their share of side effects, which can be serious and vary depending on the specific SARM, dosage, and individual factors. 

Here are some of the most concerning side effects of SARMs:

  • Liver Damage: Certain SARMs can harm the liver, potentially leading to serious health complications.
  • Cardiovascular Issues: SARMs may increase the risk of heart attack, stroke, and other cardiovascular problems.
  • Hormonal Imbalances: SARMs can disrupt natural hormone production, leading to issues like decreased libido, erectile dysfunction, and fertility problems.
  • Mood Swings and Aggression: Some SARMs can affect mood and behavior, causing irritability, aggression, and even depression.
  • Virilization in Women: Women using SARMs may experience masculinizing effects like facial hair growth and a deepened voice.

These are just some of the potential side effects of SARMs. It’s important to note that research on their long-term effects is limited, and the full extent of their risks is not yet fully understood.

Specific SARMs and their Side Effects

Not all SARMs are created equal. Each SARM has its unique set of side effects:

  • LGD-4033 (Ligandrol): Considered potent for muscle growth, but may increase the risk of liver damage and aggression.
  • Ostarine (MK-2866): Widely used for muscle gain and bone health, but potential side effects include liver damage and testosterone suppression.
  • Cardarine (GW-501516): Primarily used for endurance enhancement, but limited research raises concerns about potential risks.
  • YK-11: Emerging SARM with promising muscle-building properties, but limited data exists on its long-term effects and safety.

Individual Factors

Our bodies are unique, and we all respond differently to SARMs. Factors like genetics, age, health status, and dosage can significantly influence the side effects we experience.

For example, someone with liver problems may be more susceptible to liver damage from SARMs. Similarly, younger users may be at greater risk for certain side effects compared to older individuals.

Minimizing Risks of SARMs

If you choose to use SARMs, consult your doctor or health professional so that you get a personalised SARM that suits your body and does not have severe side effects. 

However, we’ve listed a few basic points to consider to minimize the risks of SARMs:

  • Start with a low dose and gradually increase: Begin with the lowest effective dose and monitor your body’s response. Increase the dose slowly only if necessary and with proper supervision.
  • Cycle SARMs with adequate rest periods: Don’t use SARMs continuously. Allow your body time to recover between cycles to minimize the risk of long-term side effects.
  • Choose SARMs with established safety profiles: Opt for SARMs with more research and a better understanding of their side effect profiles.
  • Monitor your health regularly: Regular blood tests and health checkups can help identify any potential side effects early on.

Alternatives to SARMs

SARMs are undoubtedly great for quick muscle building and endurance building, but some natural alternatives exist. They may not be very effective initially, but they are more healthy options in the long run. Besides, they will not harm your body in any way:

  • Resistance training: This is the cornerstone of any successful muscle-building program. Focus on compound exercises and progressively overload your muscles to stimulate growth.
  • Proper nutrition: Eating a balanced diet with adequate protein gives your body the nutrients it needs to build and repair muscle tissue.
  • Adequate sleep and rest: Your body needs sufficient rest to recover from workouts and optimize muscle growth. Aim for 7-8 hours of quality sleep each night.
  • Supplements: Certain supplements like creatine and protein powder can offer additional benefits for muscle growth, but they should never replace a balanced diet and proper training.


SARM consumption has become very popular recently. They may promise rapid muscle growth and improved performance, but their potential side effects raise serious concerns about their safety. 

Before making a decision, it is essential to consider the potential benefits and risks carefully, considering your individual health and goals.


1. How bad are SARMs side effects?

Vary depending on SARM, dosage, and individual. Common side effects include liver damage, heart problems, hormonal imbalances, mood swings, and virilization in women. Severity ranges from mild to life-threatening.

2. Do SARMs affect kidneys?

There is limited research, but animal studies suggest some SARMs may cause kidney damage. 

3. Can SARMs affect your brain?

Animal studies suggest SARMs may increase the risk of depression and anxiety. More human research is needed.

4. Do SARMs cause infertility?

Yes, SARMs can disrupt hormone production in both men and women, potentially leading to infertility.